OsCare Sono


Convenient and reliable osteoporosis risk assessment

Convenient measurement

Measurement is performed conveniently on the table top using harmless ultrasound. Apart from rolling up a sleeve, no undressing is needed. The result is obtained in a few minutes and is shown in an easy-to-interpret report.

Cost efficient and flexible

No dedicated room or specialized staff are needed. Besides ultrasound gel, there are no consumables. The measurement is quick and the small device may be easily moved between locations. OsCare Sono® is well suitable also for low threshold locations, such as high street pharmacies.

Reliable risk assessment

OsCare Sono® measurement has been shown to correlate with bone cortical thickness, elasticity and mineral density, all important determinants of bone strength. OsCare Sono® sensitively recognizes patients diagnosed osteoporotic based on DXA (dual energy X-ray).

 


Measuring with Oscare Sono®

Accurate method

The OsCare Sono® measures the speed of ultrasound lengthwise in the radius bone in the forearm. Axial speed of ultrasound is the best method for bone strength measurement, providing correlation with bone elasticity and mass density, which depend on the microporosity of the bone.

As OsCare Sono® uses a low ultrasound frequency, of about 200 kHz, which travels deeper into the bone tissue than higher frequency, the measurement also correlates with cortical thickness, providing a good overall view to bone strength. A patented algorithm helps to eliminate the effect of soft tissue.

Convenient measurement

At the start of the measurement procedure, the subject’s background information is entered into the system and the correct measurement location is defined.

The actual measurement is performed with the subject’s arm resting on the tabletop and the operator positioning the ultrasound sensor head on top of subject’s radius bone. The operator is guided in correct positioning of the sensor by a real time ultrasound waveform display to ascertain a high quality measurement.

The results are ready for counseling in less than a minute.

Easy-to-understand report

An easily understandable report is shown and may be printed or saved. The report displays the T-score, which compares the subject’s measurement result to the average result in healthy young females. Based on the T-score, the results can be divided into areas of low risk, increased risk or significantly increased risk of osteoporosis.

With a result indicating significantly increased risk, or increased risk and a presence of other osteoporosis risk factors, the subject should be further investigated with e.g. DXA for a diagnosis of osteoporosis.

 


Correlation with bone properties

The OsCare Sono® measurement results have been compared with measurement results produced with pQCT (peripheral quantitative computed tomography and pDXA (peripheral DXA) at the radius. The comparison shows good correlation of OsCare Sono® measurement results with bone mineral density in the cortex and subcortically as well as with bone cortical thickness1,2. Axial speed of ultrasound has furthermore been shown to correlate with elasticity of the bone, which is dependent on the microporosity of the bone3.


Discrimination of fractures

An important property for an osteoporosis screening device is its ability to differentiate bone that will fracture from bone that will not. The OsCare Sono® measurement has been shown to retrospectively discriminate fractures in postmenopausal women, equally well as DXA (dual energy X-ray) or pQCT (peripheral quantitative computed tomography)4.


Correlation with central DXA

OsCare Sono® sensitively recognizes patients who have been diagnosed osteoporotic based on DXA: 95% of them get a result with OsCare Sono® indicating increased or significantly increased risk of osteoporosis. Of those with increased risk of osteoporosis based on OsCare Sono®, 80 % are either osteopenic or osteoporotic. Of those with greatly increased risk, 95 % are either osteopenic or osteoporotic5.

  1. Kilappa et al. Low-frequency axial ultrasound velocity correlates with bone mineral density and cortical thickness in the radius and tibia in pre- and postmenopausal women. Osteoporos Int 22(4):1103-13, 2011.
  2. Pfaffen R et al. Assessment of a New Low Frequency Quantitative Ultrasound (QUS) of the Radius. Poster at the ISCD 2016 meeting.
  3. Raum et al. Bone microstructure and elastic tissue properties are reflected in QUS axial transmission measurements, Ultrasound in Med. & Biol. Vol 31 no 9, 2005.
  4. Moilanen et al. Discrimination of fractures by low-frequency axial transmission ultrasound in postmenopausal females. Osteoporos Int 24(2):723-730, 2013.
  5. Technical white paper: Use of OsCare Sono® for ultrasound-based osteoporosis screening, 2014; Measurements at the Center for Health Promotion Research, Tampere, Finland and at the Osteoporosis clinic Mehiläinen Oy Ympyrätalo and Kätilöopisto Maternity Hospital, Helsinki, Finland.


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